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HIF-1α regulates IL-1β and IL-17 in sarcoidosis
Sarcoidosis is a complex systemic granulomatous disease of unknown etiology characterized by the presence of activated macrophages and Th1/Th17 effector cells. Data mining of our RNA-Seq analysis of CD14(+)monocytes showed enrichment for metabolic and hypoxia inducible factor (HIF) pathways in sarco...
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| Pubblicato in: | eLife |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506207/ https://ncbi.nlm.nih.gov/pubmed/30946009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44519 |
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