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MKP-1 Negatively Regulates LPS-mediated IL-1β Production Through p38 Activation and HIF-1α Expression
Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that plays a major role in inflammatory diseases as well as cancer. The inflammatory response after Toll-like receptor (TLR) 4 activation is tightly regulated through phosphorylation of MAP kinases, including p38 and JNK pathways. The activat...
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| Опубликовано в: : | Cell Signal |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5410178/ https://ncbi.nlm.nih.gov/pubmed/28238855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.02.018 |
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