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Non‐canonical cMet regulation by vimentin mediates Plk1 inhibitor–induced apoptosis

To address the need for improved systemic therapy for non–small‐cell lung cancer (NSCLC), we previously demonstrated that mesenchymal NSCLC was sensitive to polo‐like kinase (Plk1) inhibitors, but the mechanisms of resistance in epithelial NSCLC remain unknown. Here, we show that cMet was differenti...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Singh, Ratnakar, Peng, Shaohua, Viswanath, Pavitra, Sambandam, Vaishnavi, Shen, Li, Rao, Xiayu, Fang, Bingliang, Wang, Jing, Johnson, Faye M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505578/
https://ncbi.nlm.nih.gov/pubmed/31040125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809960
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