Non‐canonical cMet regulation by vimentin mediates Plk1 inhibitor–induced apoptosis

To address the need for improved systemic therapy for non–small‐cell lung cancer (NSCLC), we previously demonstrated that mesenchymal NSCLC was sensitive to polo‐like kinase (Plk1) inhibitors, but the mechanisms of resistance in epithelial NSCLC remain unknown. Here, we show that cMet was differenti...

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Bibliografiske detaljer
Udgivet i:EMBO Mol Med
Main Authors: Singh, Ratnakar, Peng, Shaohua, Viswanath, Pavitra, Sambandam, Vaishnavi, Shen, Li, Rao, Xiayu, Fang, Bingliang, Wang, Jing, Johnson, Faye M
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505578/
https://ncbi.nlm.nih.gov/pubmed/31040125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809960
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