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Non‐canonical cMet regulation by vimentin mediates Plk1 inhibitor–induced apoptosis

To address the need for improved systemic therapy for non–small‐cell lung cancer (NSCLC), we previously demonstrated that mesenchymal NSCLC was sensitive to polo‐like kinase (Plk1) inhibitors, but the mechanisms of resistance in epithelial NSCLC remain unknown. Here, we show that cMet was differenti...

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Bibliografski detalji
Izdano u:EMBO Mol Med
Glavni autori: Singh, Ratnakar, Peng, Shaohua, Viswanath, Pavitra, Sambandam, Vaishnavi, Shen, Li, Rao, Xiayu, Fang, Bingliang, Wang, Jing, Johnson, Faye M
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505578/
https://ncbi.nlm.nih.gov/pubmed/31040125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809960
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