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Higher cMET dependence of sacral compared to clival chordoma cells: contributing to a better understanding of cMET in chordoma

Chordomas are rare slow growing, malignant bone tumors of the axial skeleton with no approved medical treatment. As the majority of chordomas express cMET and its ligand, HGF, and crosstalks between EGFR and MET-signaling exist, we aimed to explore cMET activity in chordoma cell lines and clinical s...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lohberger, Birgit, Scheipl, Susanne, Heitzer, Ellen, Quehenberger, Franz, de Jong, Danielle, Szuhai, Karoly, Liegl-Atzwanger, Bernadette, Rinner, Beate
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8203686/
https://ncbi.nlm.nih.gov/pubmed/34127734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92018-0
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