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Higher cMET dependence of sacral compared to clival chordoma cells: contributing to a better understanding of cMET in chordoma
Chordomas are rare slow growing, malignant bone tumors of the axial skeleton with no approved medical treatment. As the majority of chordomas express cMET and its ligand, HGF, and crosstalks between EGFR and MET-signaling exist, we aimed to explore cMET activity in chordoma cell lines and clinical s...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8203686/ https://ncbi.nlm.nih.gov/pubmed/34127734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92018-0 |
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