Caricamento...
Switching the activity of Cas12a using guide RNA strand displacement circuits
The CRISPR effector protein Cas12a has been used for a wide variety of applications such as in vivo gene editing and regulation or in vitro DNA sensing. Here, we add programmability to Cas12a-based DNA processing by combining it with strand displacement-based reaction circuits. We first establish a...
Salvato in:
| Pubblicato in: | Nat Commun |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504869/ https://ncbi.nlm.nih.gov/pubmed/31064995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09953-w |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|