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Mismatches Improve the Performance of Strand-Displacement Nucleic Acid Circuits()

Catalytic hairpin assembly (CHA) has previously proven useful as a transduction and amplification method for nucleic acid detection. However, the two hairpin substrates in a CHA circuit can potentially react non-specifically even in the absence of a singles-stranded catalyst, and this non-specific b...

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Detalles Bibliográficos
Main Authors: Jiang, Yu Sherry, Bhadra, Sanchita, Li, Bingling, Ellington, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983710/
https://ncbi.nlm.nih.gov/pubmed/24402831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307418
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