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A Spinach molecular beacon triggered by strand displacement
We have re-engineered the fluorescent RNA aptamer Spinach to be activated in a sequence-dependent manner. The original Spinach aptamer was extended at its 5′- and 3′-ends to create Spinach.ST, which is predicted to fold into an inactive conformation and thus prevent association with the small molecu...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2014
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4105745/ https://ncbi.nlm.nih.gov/pubmed/24942625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.045047.114 |
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