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A Sweet Spot for Molecular Diagnostics: Coupling Isothermal Amplification and Strand Exchange Circuits to Glucometers

Strand exchange nucleic acid circuitry can be used to transduce isothermal nucleic acid amplification products into signals that can be readable on an off-the-shelf glucometer. Loop-mediated isothermal amplification (LAMP) is limited by the accumulation of non-specific products, but nucleic acid cir...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Du, Yan, Hughes, Randall A., Bhadra, Sanchita, Jiang, Yu Sherry, Ellington, Andrew D., Li, Bingling
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458886/
https://ncbi.nlm.nih.gov/pubmed/26050646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11039
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