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Cryo-EM structure of the RNA-guided ribonuclease Cas12g
Cas12g, the type V-G CRISPR-Cas effector, is an RNA-guided ribonuclease that targets single-stranded RNA substrate. CRISPR-Cas12g system offers a potential platform for transcriptome engineering and diagnostic applications. We determined the structures of Cas12g-guide RNA complexes in the absence an...
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| Publicado no: | Nat Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8256697/ https://ncbi.nlm.nih.gov/pubmed/33495647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00721-2 |
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