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GRK Mediates μ-Opioid Receptor Plasma Membrane Reorganization

Differential regulation of the μ-opioid receptor (MOP) has been linked to the development of opioid tolerance and dependence which both limit the clinical use of opioid analgesics. At a cellular level, MOP regulation occurs via receptor phosphorylation, desensitization, plasma membrane redistributio...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Gondin, Arisbel B., Halls, Michelle L., Canals, Meritxell, Briddon, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504784/
https://ncbi.nlm.nih.gov/pubmed/31118885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00104
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