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Synthesis and Characterization of Site-Specific O(6)-Alkylguanine DNA-alkyl Transferase-Oligonucleotide Crosslinks
O(6)-Alkylguanine DNA-alkyltransferase (AGT), a DNA repair protein, can form crosslinks with DNA. The AGT-DNA crosslinks are known to be mutagenic when AGT is heterologously expressed in Escherichia coli, as well as in mammalian cells. To understand the biological consequences, reliable access to AG...
Enregistré dans:
| Publié dans: | Curr Protoc Nucleic Acid Chem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504252/ https://ncbi.nlm.nih.gov/pubmed/30657645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.74 |
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