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Synthesis, Antimicrobial Activity, Attenuation of Aminoglycoside Resistance in MRSA, and Ribosomal A-site Binding of Pyrene-Neomycin Conjugates

The development of new ligands that have comparable or enhanced therapeutic efficacy relative to current drugs is vital to the health of the global community in the short and long term. One strategy to accomplish this goal is to functionalize sites on current antimicrobials to enhance specificity an...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Story, Sandra, Skriba, Michael J., Maiti, Krishnagopal, Ranjan, Nihar, Degtyareva, Natalya N., Green, Keith D., Khodaverdian, Verjine, Oyelere, Adegboyega K., Garneau-Tsodikova, Sylvie, Arya, Dev P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503653/
https://ncbi.nlm.nih.gov/pubmed/30530174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2018.11.022
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