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Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase
[Image: see text] Catechol-O-methyltransferase (COMT) is a model S-adenosyl-l-methionine (SAM) dependent methyl transferase, which catalyzes the methylation of catecholamine neurotransmitters such as dopamine in the primary pathway of neurotransmitter deactivation in animals. Despite extensive study...
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| Yayımlandı: | ACS Catal |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical Society
2019
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6503465/ https://ncbi.nlm.nih.gov/pubmed/31080692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b00174 |
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