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Role of the C-terminal domain in inactivation of brain and cardiac sodium channels

Inactivation is a fundamental characteristic of Na(+) channels, and small changes cause skeletal muscle paralysis and myotonia, epilepsy, and cardiac arrhythmia. Brain Na(v)1.2a channels have faster inactivation than cardiac Na(v)1.5 channels, but minor differences in inactivation gate structure are...

詳細記述

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書誌詳細
主要な著者: Mantegazza, Massimo, Yu, Frank H., Catterall, William A., Scheuer, Todd
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC65032/
https://ncbi.nlm.nih.gov/pubmed/11742069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211563298
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