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Modulation of cardiac Na+ channels expressed in a mammalian cell line and in ventricular myocytes by protein kinase C.

Cardiac rH1 Na+ channel alpha subunits were expressed in cells of the Chinese hamster lung 1610 cell line by transfection, and a stable cell line expressing cardiac Na+ channels (SNa-rH1) was isolated. Mean Na+ currents of 2.2 +/- 1.0 nA were recorded, which corresponds to a cell surface density of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Qu, Y, Rogers, J, Tanada, T, Scheuer, T, Catterall, W A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8159741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.8.3289
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