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Role of the C-terminal domain in inactivation of brain and cardiac sodium channels
Inactivation is a fundamental characteristic of Na(+) channels, and small changes cause skeletal muscle paralysis and myotonia, epilepsy, and cardiac arrhythmia. Brain Na(v)1.2a channels have faster inactivation than cardiac Na(v)1.5 channels, but minor differences in inactivation gate structure are...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The National Academy of Sciences
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC65032/ https://ncbi.nlm.nih.gov/pubmed/11742069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211563298 |
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