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Molecular Analysis of the Putative Inactivation Particle in the Inactivation Gate of Brain Type IIA Na(+) Channels

Fast Na(+) channel inactivation is thought to involve binding of phenylalanine 1489 in the hydrophobic cluster IFM in L(III-IV )of the rat brain type IIA Na(+) channel. We have analyzed macroscopic and single channel currents from Na(+) channels with mutations within and adjacent to hydrophobic clus...

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Detalhes bibliográficos
Main Authors: Kellenberger, Stephan, West, James W., Scheuer, Todd, Catterall, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217064/
https://ncbi.nlm.nih.gov/pubmed/9154906
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