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Molecular Analysis of Potential Hinge Residues in the Inactivation Gate of Brain Type IIA Na(+) Channels

During inactivation of Na(+) channels, the intracellular loop connecting domains III and IV is thought to fold into the channel protein and occlude the pore through interaction of the hydrophobic motif isoleucine-phenylalanine-methionine (IFM) with a receptor site. We have searched for amino acid re...

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Detalhes bibliográficos
Main Authors: Kellenberger, Stephan, West, James W., Catterall, William A., Scheuer, Todd
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217067/
https://ncbi.nlm.nih.gov/pubmed/9154907
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