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USP7: Novel Drug Target in Cancer Therapy
Ubiquitin specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUB) that erases ubiquitin and protects substrate protein from degradation. Full activity of USP7 requires the C-terminal Ub-like domains fold back onto the catalytic domain, allowing the remodeling of the active site to a...
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| Veröffentlicht in: | Front Pharmacol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6502913/ https://ncbi.nlm.nih.gov/pubmed/31114498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00427 |
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