USP8 Inhibitor Suppresses HER-2 Positive Gastric Cancer Cell Proliferation and Metastasis via the PI3K/AKT Signaling Pathway

PURPOSE: Referring to global cancer statistics, the incidence of gastric cancer (GC) was ranked sixth; however, detailed mechanisms underlying its development were not thoroughly investigated. Previous studies have reported that inhibition of ubiquitin-specific peptidase 8 (USP8) induced degradation...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Sun, Jiangang, Shen, Dandan, Zheng, Yichao, Ren, Hongmei, Liu, Hongmin, Chen, Xiaoping, Gao, Yongshun
Format: Artigo
Language:Inglês
Published: Dove 2020
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547803/
https://ncbi.nlm.nih.gov/pubmed/33116578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S271496
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