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Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation

BACKGROUND: Ubiquitin specific peptidase 8 (USP8) has been reported to induce the degradation of several receptor tyrosine kinases such as epidermal growth factor receptor (EGFR), among which human epidermal growth factor receptor-3 (HER-3) is one of them. However, the role and functional mechanisms...

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Publicat a:Onco Targets Ther
Autors principals: Sun, Jiangang, Shen, Dandan, Gao, Yongshun, Zheng, Yichao, Zhao, Lijuan, Maa, Mamum, Liu, Hongmin, Chen, Xiaoping
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7429216/
https://ncbi.nlm.nih.gov/pubmed/32848421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S264108
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