BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

Mitochondria and cytochrome c release play a role in the death of neurons and glia after cerebral ischemia. In the present study, we investigated whether BID, a proapoptotic promoter of cytochrome c release and caspase 8 substrate, was expressed in brain, activated after an ischemic insult in vivo a...

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Autors principals: Plesnila, Nikolaus, Zinkel, Sandra, Le, Dean A., Amin-Hanjani, Sepideh, Wu, Yonqin, Qiu, Jianhua, Chiarugi, Alberto, Thomas, Sunu S., Kohane, Daniel S., Korsmeyer, Stanley J., Moskowitz, Michael A.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC65027/
https://ncbi.nlm.nih.gov/pubmed/11742085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.261323298
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