Proapoptotic BID is required for myeloid homeostasis and tumor suppression

The proper expansion and contraction of hematopoietic cells requires tight regulation of cell death. BID, a “BH3-only” molecule, amplifies death receptor signals connecting the extrinsic to intrinsic pathways by triggering the mitochondrial pathway of apoptosis. Bid-deficient mice, as they age, spon...

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Dades bibliogràfiques

Publicat a:	Genes Dev
Autors principals:	Zinkel, Sandra S., Ong, Christy C., Ferguson, David O., Iwasaki, Hiromi, Akashi, Koichi, Bronson, Roderick T., Kutok, Jeffery L., Alt, Frederick W., Korsmeyer, Stanley J.
Format:	Artigo
Idioma:	Inglês
Publicat:	Cold Spring Harbor Laboratory Press 2003
Matèries:	Research Paper
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12533511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1045603
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