Proapoptotic BID is required for myeloid homeostasis and tumor suppression
The proper expansion and contraction of hematopoietic cells requires tight regulation of cell death. BID, a “BH3-only” molecule, amplifies death receptor signals connecting the extrinsic to intrinsic pathways by triggering the mitochondrial pathway of apoptosis. Bid-deficient mice, as they age, spon...
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| Publicado no: | Genes Dev |
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| Principais autores: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC195974/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12533511/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1045603 |
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