Protective Effects of Statins after Embolic Focal Cerebral Ischemia in Endothelial Nitric Oxide Synthase Knockout Mice

Previous studies have shown that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) protect brain against ischemic injury by upregulating endothelial nitric oxide synthase (eNOS). Here, we tested the hypothesis that statins provide additional beneficial effects by upregul...

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Detalhes bibliográficos
Main Authors: Asahi, Minoru, Thomas, Sunu, Yoshimura, Shin-ichi, Sumii, Toshihisa, Mori, Tatsuro, Qiu, Jianhua, Amin-Hanjani, Sepideh, Huang, Paul L., Liao, James K., Lo, Eng H., Moskowitz, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742229/
https://ncbi.nlm.nih.gov/pubmed/15716855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600070
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