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Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation
Caspase-3 is a major cell death effector protease in the adult and neonatal nervous system. We found a greater number and higher density of cells in the cortex of caspase-3(−/−) adult mice, consistent with a defect in developmental cell death. Caspase-3(−/−) mice were also more resistant to ischemic...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137565/ https://ncbi.nlm.nih.gov/pubmed/12415117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232473399 |
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