Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

We examined the expression, activation, and cellular localization of caspase-3 (CPP32) using immunohistochemistry, immunoblots, and cleavage of the fluorogenic substrateN-benzyloxycarbonyl-Asp-Glu-Val-Asp-7-amino-4-trifluoromethyl coumarin (zDEVD-afc) in adult mouse brain after temporary (2 hr) midd...

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Pubblicato in:J Neurosci
Autori principali: Namura, Shobu, Zhu, Jinmin, Fink, Klaus, Endres, Matthias, Srinivasan, Anu, Tomaselli, Kevin J., Yuan, Junying, Moskowitz, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1998
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793169/
https://ncbi.nlm.nih.gov/pubmed/9570797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-10-03659.1998
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