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Synergistic effects of caspase inhibitors and MK-801 in brain injury after transient focal cerebral ischaemia in mice
1. Excitotoxic and apoptotic mechanisms have been implicated in the pathophysiology of cerebral ischaemia. Both MK-801, an NMDA receptor antagonist, or peptide inhibitors of the caspase family (z-VAD.FMK and z-DEVD.FMK), protect mouse brain from ischaemic cell damage. In this study, we examined whet...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565432/ https://ncbi.nlm.nih.gov/pubmed/9690868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0701871 |
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