Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia

1. We tested the hypothesis that combined use of trophic factors and caspase inhibitors increases brain resistance to ischaemia in mice. 2. Intracerebroventricular administration of bFGF (>10 ng) 30 min after MCA occlusion decreased infarct size and neurological deficit in a dose-dependent manner...

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Bibliografiske detaljer
Main Authors: Ma, Jianya, Qiu, Jianhua, Hirt, Lorenz, Dalkara, Turgay, Moskowitz, Michael A
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572791/
https://ncbi.nlm.nih.gov/pubmed/11375250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704075
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