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Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia
1. We tested the hypothesis that combined use of trophic factors and caspase inhibitors increases brain resistance to ischaemia in mice. 2. Intracerebroventricular administration of bFGF (>10 ng) 30 min after MCA occlusion decreased infarct size and neurological deficit in a dose-dependent manner...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1572791/ https://ncbi.nlm.nih.gov/pubmed/11375250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704075 |
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