Signaling characteristics and functional regulation of delta opioid-kappa opioid receptor (DOP-KOP) heteromers in peripheral sensory neurons

Receptor heteromers often display distinct pharmacological and functional properties compared to the individual receptor constituents. In this study, we compared the properties of the DOP-KOP heteromer agonist, 6’-guanidinonaltrindole (6’-GNTI), with agonists for DOP ([D-Pen2,5]-enkephalin [DPDPE])...

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Udgivet i:Neuropharmacology
Main Authors: Jacobs, Blaine A., Pando, Miryam M., Jennings, Elaine M., Jamshidi, Raehannah J., Zamora, Joshua C., Chavera, Teresa S., Clarke, William P., Berg, Kelly A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500751/
https://ncbi.nlm.nih.gov/pubmed/30776373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2019.02.019
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