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Constitutive Desensitization of Opioid Receptors in Peripheral Sensory Neurons
Opioid receptors expressed by peripheral pain-sensing neurons are functionally inactive for antinociceptive signaling under most basal conditions; however, tissue damage or exposure to inflammatory mediators (e.g., bradykinin) converts these receptors from a nonresponsive state to a functionally com...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118646/ https://ncbi.nlm.nih.gov/pubmed/27660244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232835 |
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