Constitutive Desensitization of Opioid Receptors in Peripheral Sensory Neurons

Opioid receptors expressed by peripheral pain-sensing neurons are functionally inactive for antinociceptive signaling under most basal conditions; however, tissue damage or exposure to inflammatory mediators (e.g., bradykinin) converts these receptors from a nonresponsive state to a functionally com...

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Bibliografske podrobnosti
izdano v:J Pharmacol Exp Ther
Main Authors: Sullivan, Laura C., Chavera, Teresa S., Jamshidi, Raehannah J., Berg, Kelly A., Clarke, William P.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2016
Teme:
Cellular and Molecular
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118646/
https://ncbi.nlm.nih.gov/pubmed/27660244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232835
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