Functional Selectivity of Kappa Opioid Receptor Agonists in Peripheral Sensory Neurons

Activation of kappa opioid receptors (KORs) expressed by peripheral sensory neurons that respond to noxious stimuli (nociceptors) can reduce neurotransmission of pain stimuli from the periphery to the central nervous system. We have previously shown that the antinociception dose-response curve for p...

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Détails bibliographiques
Publié dans:J Pharmacol Exp Ther
Auteurs principaux: Jamshidi, Raehannah J., Jacobs, Blaine A., Sullivan, Laura C., Chavera, Teresa A., Saylor, Rachel M., Prisinzano, Thomas E., Clarke, William P., Berg, Kelly A.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2015
Sujets:
Cellular and Molecular
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613959/
https://ncbi.nlm.nih.gov/pubmed/26297384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.225896
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