Functional Selectivity of Kappa Opioid Receptor Agonists in Peripheral Sensory Neurons

Activation of kappa opioid receptors (KORs) expressed by peripheral sensory neurons that respond to noxious stimuli (nociceptors) can reduce neurotransmission of pain stimuli from the periphery to the central nervous system. We have previously shown that the antinociception dose-response curve for p...

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Publicado en:J Pharmacol Exp Ther
Autores principales: Jamshidi, Raehannah J., Jacobs, Blaine A., Sullivan, Laura C., Chavera, Teresa A., Saylor, Rachel M., Prisinzano, Thomas E., Clarke, William P., Berg, Kelly A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2015
Materias:
Cellular and Molecular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613959/
https://ncbi.nlm.nih.gov/pubmed/26297384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.115.225896
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