Á lódáil...
Unified energetics analysis unravels SpCas9 cleavage activity for optimal gRNA design
While CRISPR/Cas9 is a powerful tool in genome engineering, the on-target activity and off-target effects of the system widely vary because of the differences in guide RNA (gRNA) sequences and genomic environments. Traditional approaches rely on separate models and parameters to treat on- and off-ta...
Na minha lista:
| Foilsithe in: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
National Academy of Sciences
2019
|
| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6500161/ https://ncbi.nlm.nih.gov/pubmed/30988204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820523116 |
| Clibeanna: |
Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!
|