Study of the effect of the introduction of mitochondrial import determinants into the gRNA structure on the activity of the gRNA/SpCas9 complex in vitro

It has long been known that defects in the structure of the mitochondrial genome can cause various neuromuscular and neurodegenerative diseases. Nevertheless, at present there is no effective method for treating mitochondrial diseases. The major problem with the treatment of such diseases is associa...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: E. G. Zakirova, Y. V. Vyatkin, N. A. Verechshagina, V. V. Muzyka, I. O. Mazunin, K. E. Orishchenko
格式: Artigo
語言:Inglês
出版: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2020-08-01
叢編:Vavilovskij Žurnal Genetiki i Selekcii
主題:
mitochondrial dna
crispr/cas9
the mitochondrial import determinants
heteroplasmy
在線閱讀:https://vavilov.elpub.ru/jour/article/view/2715
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍