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An enantioselective synthesis of α-alkylated pyrroles via cooperative isothiourea/palladium catalysis.

Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in...

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書目詳細資料
發表在:Org Biomol Chem
Main Authors: Scaggs, W. Rush, Scaggs, Toya D., Snaddon, Thomas N.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499370/
https://ncbi.nlm.nih.gov/pubmed/30483696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02600a
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