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An enantioselective synthesis of α-alkylated pyrroles via cooperative isothiourea/palladium catalysis.
Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in...
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| Опубликовано в: : | Org Biomol Chem |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499370/ https://ncbi.nlm.nih.gov/pubmed/30483696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob02600a |
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