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Enantioselective Synthesis of α‐Aryl‐β(2)‐Amino‐Esters by Cooperative Isothiourea and Brønsted Acid Catalysis
The synthesis of α‐aryl‐β(2)‐amino esters through enantioselective aminomethylation of an arylacetic acid ester in high yields and enantioselectivity via cooperative isothiourea and Brønsted acid catalysis is demonstrated. The scope and limitations of this process are explored (25 examples, up to 94...
Tallennettuna:
| Julkaisussa: | Angew Chem Int Ed Engl |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
John Wiley and Sons Inc.
2021
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8252622/ https://ncbi.nlm.nih.gov/pubmed/33646631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202016220 |
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