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The Recognition of Unrelated Ligands by Identical Proteins
Unrelated ligands, often found in drug discovery campaigns, can bind to the same receptor, even with the same protein residues. To investigate how this might occur, and whether it might be typically possible to find unrelated ligands for the same drug target, we sought examples of topologically unre...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499068/ https://ncbi.nlm.nih.gov/pubmed/30095890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00443 |
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