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The Recognition of Identical Ligands by Unrelated Proteins
The binding of drugs and reagents to off-targets is well-known. Whereas many off-targets are related to the primary target by sequence and fold, many ligands bind to unrelated pairs of proteins, and these are harder to anticipate. If the binding site in the off-target can be related to that of the p...
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| 出版年: | ACS Chem Biol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4684825/ https://ncbi.nlm.nih.gov/pubmed/26421501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00683 |
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