ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcomes. 4-Amino-2-trifluoromethyl-phenyl retin...

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Detalles Bibliográficos
Publicado en:Biol Res
Autores principales: Feng, Yubin, Hua, Xiaoxiao, Niu, Ruowen, Du, Yan, Shi, Congjian, Zhou, Renpeng, Chen, Fei-Hu
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498685/
https://ncbi.nlm.nih.gov/pubmed/31053167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-019-0232-9
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