Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway

Paclitaxel, a taxane, is a cytotoxic chemotherapeutic agent that targets microtubules. It has become a front-line therapy for a broad range of malignancies, including lung, breast, gastric, esophageal, and bladder carcinomas. Although paclitaxel can inhibit tumor development and improve survival, po...

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Vydáno v:Oncotarget
Hlavní autoři: Wang, Sai-Qi, Wang, Cong, Chang, Li-Ming, Zhou, Kai-Rui, Wang, Jun-Wei, Ke, Yu, Yang, Dong-Xiao, Shi, Hong-Ge, Wang, Ran, Shi, Xiao-Li, Ma, Li-Ying, Liu, Hong-Min
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341958/
https://ncbi.nlm.nih.gov/pubmed/27659528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12166
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