ROS play an important role in ATPR inducing differentiation and inhibiting proliferation of leukemia cells by regulating the PTEN/PI3K/AKT signaling pathway

BACKGROUND: Acute myeloid leukemia (AML) is an aggressive and mostly incurable hematological malignancy with frequent relapses after an initial response to standard chemotherapy. Therefore, novel therapies are urgently required to improve AML clinical outcomes. 4-Amino-2-trifluoromethyl-phenyl retin...

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Dades bibliogràfiques
Publicat a:Biol Res
Autors principals: Feng, Yubin, Hua, Xiaoxiao, Niu, Ruowen, Du, Yan, Shi, Congjian, Zhou, Renpeng, Chen, Fei-Hu
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498685/
https://ncbi.nlm.nih.gov/pubmed/31053167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-019-0232-9
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