PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis

PI3K/AKT/PTEN pathway is important in the regulation of angiogenesis mediated by vascular endothelial growth factor in many tumors including leukemia. The signaling pathway is activated in leukemia patients as well as leukemia cell lines together with a decrease in the expression of PTEN gene. The m...

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Detalles Bibliográficos
Main Authors: Okumura, Naoko, Yoshida, Hitomi, Kitagishi, Yasuko, Murakami, Mutsumi, Nishimura, Yuri, Matsuda, Satoru
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299269/
https://ncbi.nlm.nih.gov/pubmed/22505939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/843085
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