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Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy

Multiple enzymes participate in the phosphorylation of a group of phosphoinositide lipids. Because of their important role in signal transduction, the dysregulated metabolism of phosphoinositides represents a key step in many disease settings. Loss of their function has been demonstrated to occur as...

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Bibliografiske detaljer
Main Authors: Matsuda, Satoru, Nakanishi, Atsuko, Wada, Yoko, Kitagishi, Yasuko
Format: Artigo
Sprog:Inglês
Udgivet: Bentham Open 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821079/
https://ncbi.nlm.nih.gov/pubmed/24222802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1874104501307010023
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