PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis

PI3K/AKT/PTEN pathway is important in the regulation of angiogenesis mediated by vascular endothelial growth factor in many tumors including leukemia. The signaling pathway is activated in leukemia patients as well as leukemia cell lines together with a decrease in the expression of PTEN gene. The m...

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Библиографические подробности
Главные авторы: Okumura, Naoko, Yoshida, Hitomi, Kitagishi, Yasuko, Murakami, Mutsumi, Nishimura, Yuri, Matsuda, Satoru
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2012
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Review Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299269/
https://ncbi.nlm.nih.gov/pubmed/22505939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/843085
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