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Ipriflavone attenuates the degeneration of cartilage by blocking the Indian hedgehog pathway
BACKGROUND: To determine if ipriflavone, a novel and safe inhibitor of Indian hedgehog (Ihh) signaling, can attenuate cartilage degeneration by blocking the Ihh pathway. METHODS: Human chondrocytes were used to evaluate Ihh signaling, cell proliferation, apoptosis, gene, and protein expression of ch...
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| Publicado no: | Arthritis Res Ther |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6498579/ https://ncbi.nlm.nih.gov/pubmed/31046827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-019-1895-x |
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