Activation of Indian Hedgehog Promotes Chondrocyte Hypertrophy and Upregulation of MMP-13 in Human Osteoarthritic Cartilage

OBJECTIVE: The objectives of this study were to 1) determine the correlation between osteoarthritis (OA) and Ihh expression, and 2) establish the effects of Ihh on expression of markers of chondrocyte hypertrophy and MMP-13 in human OA cartilage. DESIGN: OA cartilage and synovial fluid samples were...

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Detalhes bibliográficos
Main Authors: Wei, Fangyuan, Zhou, Jingming, Wei, Xiaochun, Zhang, Juntao, Fleming, Braden C., Terek, Richard, Pei, Ming, Chen, Qian, Liu, Tao, Wei, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374008/
https://ncbi.nlm.nih.gov/pubmed/22469853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2012.03.010
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